What is neoadjuvant therapy?

Neoadjuvant therapy refers to the treatment that is administered before the primary treatment, such as surgery, with the specific goal of shrinking the tumor to make it more amenable to the subsequent definitive treatment. This approach is particularly beneficial in cases where a tumor is too large or has spread locally, as it can reduce the size of the tumor, allowing for less extensive surgery or making the tumor operable when it otherwise might not be.

The use of neoadjuvant therapy can also provide an opportunity to assess the tumor's response to the treatment, which can inform future decisions regarding postoperative therapies. Common modalities for neoadjuvant therapy include chemotherapy, radiation therapy, or targeted therapies, depending on the specific type of cancer being treated.

This strategy not only aims to enhance surgical outcomes but could also potentially reduce the likelihood of recurrence after surgery, thus improving overall patient prognosis. Understanding the role of neoadjuvant therapy is vital in managing certain cancers effectively and can be an essential part of a comprehensive treatment plan.